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A Harder Look at Alzheimer’s Causes and Treatments

In March 2019 biotechnology giant Biogen stopped two big trials of its experimental Alzheimer’s disease drug aducanumab because it did not appear to improve memory in declining patients. Then, in a surprise reversal several months later, the company and its partner, Japanese drugmaker Eisai, said they would ask the U.S. Food and Drug Administration to […]

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Machine That Keeps Livers Alive for a Week Can Repair Damaged Organs

Scientific American May 2020 A new device could ultimately increase the number of usable livers for transplants and could perhaps preserve other types of organs More than 1,000 people in the U.S. died while waiting for a liver transplant in 2018, partly because standard preservation methods can keep a donor liver alive outside the body […]

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Coronavirus: More Is Different – Scientific American Blog Network

In trying to make sense of this rapidly changing COVID-19 world, I reflected on the recent passing of one of the great physicists of our time, my former Princeton colleague and Nobel laureate, the late Phil Anderson. Anderson made seminal contributions to our understanding of fundamental interactions that make up matter, but to many scientists […]

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Genetic Engineering Could Make a COVID-19 Vaccine in Months Rather Than Years

On January 10, when Chinese researchers published the genome of a mysterious, fast-spreading, virus, it confirmed Dan Barouch’s greatest worry. The genome was similar to that of the coronavirus that caused the 2003 SARS outbreak, yet it also had striking differences. “I realized immediately that no one would be immune to it,” says Barouch, director of […]

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Science News Briefs From Around the World

Mount Vesuvius and the surrounding region, photographed from the International Space Station, January 30, 2017. Credit: Earth Observatory, NASA Here are a few brief reports about science and technology from around the planet, including one about what the eruption of Mount Vesuvius might have done to one ill-fated resident of Herculaneum. Rights & Permissions ABOUT […]

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How the COVID-19 Pandemic Could End

We know how the COVID-19 pandemic began: Bats near Wuhan, China, hold a mix of coronavirus strains, and sometime last fall one of the strains, opportunistic enough to cross species lines, left its host or hosts and ended up in a person. Then it was on the loose. What no one knows yet is how […]

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‘Spider-Man’ Immune Response May Promote Severe COVID-19

The menagerie of immune cells and proteins that defend the human body have received mounting scrutiny in struggles to ward off COVID-19. A lot of the debate has centered around whether, after recovery, a person carrying antibodies can safely return to the workplace. But attention has also turned to runaway immune reactions provoked by the […]